THYROID FNAC THESIS

Duration of complaints ranged from six days to twenty years and mean duration was 1. Inclusion criteria included clinically detected solitary thyroid nodule and euthyroid patients with normal thyroid function tests. Fine needle aspiration cytology is a simple, easy to perform, cost effective, and easily repeated procedure for the diagnosis of thyroid cancer. View at Google Scholar N. Choline Chol to creatine Cr ratio was assessed at and TEs on each nodule. Introduction Solitary thyroid nodule is defined clinically as the localised thyroid enlargement with apparently normal rest of the gland. Moreover, patient’s with contraindication for MRI such as claustrophobia and also being pace maker were excluded.

O Box Gulu – Uganda. To estimate the sensitivity and specificity of FNAC in detecting malignancy for thyroid disease using histopathology as the gold standard. Hong Kong Med J. Sinna EA, Ezzat N. The aim of this study was to estimate the sensitivity and specificity of FNAC in detecting malignancy for thyroid disease using histopathology as the gold standard. Combined 99 mTc-methoxyisobutylisonitrile scintigraphy and fine-needle aspiration cytology offers an accurate and potentially cost-effective investigative strategy for the assessment of solitary or dominant thyroid nodules.

Quality control was assured by maintaining that FNB procurement, processing and reporting was done by experienced cytopathologists using thgroid Bethesda system for reporting thyroid cytopathologythe histopathologist examining excised thyroid specimens was blinded to preoperative diagnosis with FNAC and the cytopathologists and histopathologists for FNAC and histopathology of excised specimens respectively were generally the same for both the retrospective and prospective arms of the study thus minimizing inter-observer bias.

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Materials and methods Study design This was a cross sectional study with both prospective and retrospective arms carried out from January to April View at Google Scholar M.

Fine Needle Aspiration Cytology FNAC has been in use since the s and is a safe, cost effective method of diagnosing thyroid nodules 3.

Using a thorough clinical examination, ultrasound and FNAC, a surgeon can reliably diagnose malignancy in thyroid glands and choose appropriate surgery for the treatment of the same. In total, the numbers of cases especially cancers in this series is low and further studies with a larger fanc would give much greater confidence that the technique was worth pursuing in clinical practice. View at Google Scholar R.

thyroid fnac thesis

Malignancy was noted in 13 Indexed in Web of Science. Characterizing thyroid disease and identifying barriers to care and treatment in Uganda. Open in a separate window. MHB supervised the research.

Solitary thyroid nodule is defined clinically as the localised thyroid enlargement with apparently normal rest of the gland. Fine needle aspiration cytology is a simple, easy to perform, cost effective, and easily repeated procedure for the diagnosis of thyroid cancer.

In term of imaging, ultrasonography, as a main modality in the management of patients with thyroid nodules, has some very useful discriminatory values in distinguishing benign from malignant lesion 47 Histopathological pattern of diagnoses in patients undergoing thyroid operations.

Comparison of results of present study with various previous studies is shown in Table 7. Galectin-3 immunostaining in cytological and histopathological diagnosis of thyroid lesions. These htesis schedules were least informative due to variability of sensitivity and least reproducibility.

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A 23Fr gauge needle attached to a 10 ml syringe was inserted into the nodule.

In term of metabolite profile assessment, choline peak at 3. In a related study in Uganda, FTC predominated at Patients rhesis underwent clinical and laboratory evaluation and thyroidectomy at Mulago National Referral hospital and the Pathology department of Makerere University College of Health Sciences were consecutively recruited over a four months period.

Journal of Thyroid Research

Biopsy maneouvre was terminated when fluid appeared in the hub of the needle. Among 23 benign lesions, none showed choline peak at 3. The creatinine peak indicates energy state of the cell 14 Clinical examination, fine-needle aspiration cytology, goiter, histopathology, malignancy, ultrasonography.

thyroid fnac thesis

In vivo 1H MR spectroscopy of thyroid carcinoma. Sensitivity and specificity were The findings were compared with histopathology of fna specimens. Maharajan r Ch, Rao H.

The Accuracy of Manual Fine Needle Aspiration Cytology in the Evaluation of Thyroid Cancer

Findings on fine-needle aspiration cytology Click here to view. Patients with previous thyroid surgery, known malignant disease or history of radiation were excluded. Thess is, however, not without limitations; accuracy is lower in suspicious cytology and in follicular neoplasms. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive value were calculated for neoplastic and carcinomatous lesions.

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