Results Sixty patients were recruited. The objective of this study is to evaluate the effect of intravenous esmolol infusion on intraoperative and postoperative analgesic consumptions as well as its effect on depth of anaesthesia. We found that dexmedetomidine prolongs duration of motor block, provides safe and effective sedation without increasing the incidence of side effect in the patients under spinal anesthesia. However, this form of surgery can cause damage to the body. Dexmedetomidine premedication has provided satisfactory conditions for fiberoptic intubation and attenuated the hemodynamic response of fiberoptic intubation than the propofol group. As duration of the surgery is short and the patients have nasal packs, it is prudent to use an anesthestic technique with an early predictable recovery.

We compared the amnesic action, recovery process, and satisfaction of patients and surgeons after the use of 2 different sedation regimens for 40 patients undergoing scheduled implant surgery. A comparative study to evaluate the efficacy of dexmedetomidine as a hypotensive agent in comparison to esmolol in Functional Endoscopic Sinus Surgery FESS. Surgeon’s satisfaction was significantly higher in Dex group at the end of surgery. Dexmedetomidine infusion during middle ear surgery under general anaesthesia to provide oligaemic surgical field: For those who actually want to do a Worthwhile Thesis Something really great – Well then you need to read up a lot, ask your guide for help, go through a lot of literature before settling for something and then be prepared to do a bit more effort in convincing the Institutional Review Board to allow your Plan of Thesis and in Preparing your thesis from scratch. Full Text Available One-lung ventilation in thoracic surgery provokes profound systemic inflammatory responses and injury related to lung tidal volume changes.

Enzyme-inducing anticonvulsants increase plasma clearance of dexmedetomidine: Dexmedetomidine resulted to be as effective as propofol and midazolam in maintaining the target depth of sedation in ICU patients. The aim of the study was to determine whether or not dexmedetomidine- DEX- based intravenous infusion in dental implantation can provide better sedation and postoperative analgesia via suppressing postoperative inflammation and oxidative stress. The median age was 16 months range, 0.


Administering anesthetics to the obese population requires caution because of a variety of reasons including possible interactions with the inflammatory process observed in obese patients. Thirty-one patients were successfully extubated while receiving the dexmedetomidine infusion.

Lumbar epidural anesthesia was randomly induced as follows: Cost of dexmedetomidine therapy and debate as to the proper duration of use has brought its use to dexmedetomidie forefront of discussion. A visual analogue scale VAS was used to measure each patient’s level of pain at 1, 3, 6, 12, and 24 hours after surgery. Being new to the field they dont have much idea about the sort of topics to choose.

This study in severely burned pediatric subjects dexmedetkmidine the hemodynamic consequences of dexmedetomidine Dex administration. An exaggerated inflammatory response to tissue injury, ischemia, and reperfusion injuries can all result in excessive production of free radicals [ 51 ].

Oxidative Medicine and Cellular Longevity

Patients received epidural 0. This was a retrospective cohort study of adult patients who received dexmedetomidine for ICU sedation while on mechanical ventilation at a bed not-for-profit community hospital.

dexmedetomidine thesis topics

The operating room temperature when patients arrived and patients’ temperature when they arrived at the operating room were statistically significant to affect the occurrence of hypothermia. Full Text Available Patients with Klippel-Feil Syndrome KFS have congenital fusion of their cervical vertebrae due to a failure in the normal segmentation of the cervical vertebrae during the early weeks of gestation and also have myriad of other associated anomalies.

Children in group S received sevoflurane anethesia alone, and dexmedetomidine was replaced by the same volume of physiological saline. It is near ideal hypotensive agent used for controlled hypotension. DEX has similar pharmacokinetics in all age groups. Thirty-six evaluable infants, months old, postoperative from open heart surgery requiring mechanical ventilation.

dexmedetomidine thesis topics

The critical aspect of awake craniotomy is to maintain adequate analgesia and sedation, hemodynamic stability, airway safety, while keeping the patient immobile for duration of surgery, dexkedetomidine for neurological testing. The latency and anesthesia time min were measured.


intraoperative dexmedetomidine infusion: Topics by

The mean duration of mechanical ventilation with dexmedetomidine was numerically shorter than with propofol and significantly shorter than with midazolam. Future randomized studies will determine the role of dexmedetomidine dexjedetomidine the pain management of obese adolescents undergoing bariatric surgery.

Tertiary pediatric cardiac ICU. Furthermore, we discuss its potential indications, benefits and adverse There was a correlation between the protective effect on the brain and the dose of dexmedetomidine. In our study, VAS pain score was below about 4 in both groups during and after implant surgery. Behavior in postanesthesia care unit was rated on the four-point agitation scale.

Dexmedetomidine administration in infants following open heart surgery can provide improved sedation with reduction in supplemental medication requirements, leading to successful extubation while receiving a continuous infusion. A double-blind randomised trial. Both dexmedetomidine and labetalol had favorable effects on hemodynamics at time of emergence from anesthesia in comparison with control group without prolongation of the time of extubation.

Full Text Available An awake craniotomy is a continuously evolving technique used for the resection of brain tumours from the eloquent cortex. Patient and operative characteristics were compared between those who received intraoperative dexmedetomidine and those who did not. Power analysis was carried out before the initiation of study. Patients receiving dexmedetomidine infusion had statistically significant lesser bleeding at surgical field P Dexmedetomidine infusion can be safely used to provide oligaemic surgical field for better visualization using operating microscope for middle ear surgery.

It seems that dexmedetomidine administration during induction and surgery can cause significant reduction in most of the common arrhythmias in off-pump coronary bypass surgery.

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