Of these five cases, three flaps provided complete cover with scarring per primam patients no. Treatment with Mohs micrographic surgery vs amputation. Principes de traitement chirurgical de l’infection osseuse. This ulceration had developed in four out of seven patients from a chronic fistula case no. Case report and literature review ‘ Archives of Physical Medicine and Rehabilitation , vol. A Marjolin’s ulcer describes malignant degeneration in any chronic wound.

The notion of anatomical compartment is difficult to apply to these lesions in evaluating tumor extension, even more so because the tumor in the present case is fistulized. One of our patients no. In the majority of cases, this is squamous-cell carcinoma. Int Orthop, , 25, Eur J Vasc Surg, , 6, View at Google Scholar M.

Rev Rhum Engl Ed,63, In this report, we describe the case of a female patient who was burned 42 years prior, with a large ulceration on her back.

Marjolin’s Ulcers: A Case Series and Literature Review.

The histological analysis of the excised specimens reviea five cases of differentiated and mature spinocellular squamous-cell carcinoma and two cases of differentiated and mature verrucous squamous-cell carcinoma. Arch Phys Med Rehabil,67, Click here to see the Library ] ] can be applied to these lesions in the same way as for sarcomas, but certain differences should be noted.

marjolins ulcers a case series and literature review

Access to Document Link to publication in Scopus. Squamous cell marjolinx is the most prevalent malignancy identified in Marjolin’s ulcers and was confirmed in all patients in this study. Rev Prat,32, To receive news and publication updates for Case Reports in Otolaryngology, enter your email address in the box below.


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Click here to see the Library ] reported 50 cases of squamous-cell carcinoma that developed in chronic osteitis: Squamous cell carcinoma as a complication of chronic osteomyelitis. Most of the lesions presented as budding malodorous ulcers. On x-ray, six patients presented signs of bone invasion with the appearance of evolving osteolysis at the fistula and skin lesions patients no.

marjolins ulcers a case series and literature review

Chir Organi Mov,84, Click here to see the Library ] original description corresponded to chronic ulcers of vascular origin and it was only inafter the publication of Sedlin and Fleming’s [ 3 S edlin E, F leming J: A high index of suspicion should be considered in the presence of chronic ulcers persisting longer than 3 months; rolled or everted wound margins; foul-smelling discharge; and an increase in pain, ulcer size, or bleeding [ 79182224 ].

Radical surgical treatment for Marjolin ulcer occurring after chronic osteomyelitis.

RBCP – Pleomorphic sarcoma in Marjolin ‘s ulcer

In the present series, the inclusion criteria were the association of a chronic skin lesion related to a chronic bone infection and positive histology for squamous-cell carcinoma. The images of extended osteolysis can be related to the tumor extension but are also frequently found in cases of chronic bone infections Fig. Natl Cancer Inst,84, Indian J Cancer,33, Personal information regarding our website’s visitors, including their identity, is confidential.


Malignant degeneration of chronic wound inflammation is a rare complication that almost always develops late. Malignant lesions arising in chronic osteomyelitis.

Rev Chir Orthop,79, I kic D, P adovan I: J Burn Amd Rehabil,12, Click here to see the Library ] ]: Analysis of etiological factors of squamous cell skin cancer of different locations. J Bone Joint Surg Am, 45, Biopsy material should be obtained whenever there is a modification leading to the development of a fistula or the ulcrs of scar tissue over a focus of chronic osteitis.

marjolins ulcers a case series and literature review

Many studies have recommended biopsies of multiple areas, such as the centre and margins [ 19 ], at appropriate depths [ 11 ]. When diaphyseal resection is necessary, stabilization is obtained using an external fixator and a bone graft is associated.

However, acute malignant transformations to SCC do occur [ 51019 ]. South Med J,98, J Foot Surg,20,

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